HER2 is an actionable biomarker in advanced GI cancers.1

Dual-targeted bispecific antibodies may work in a unique way to eliminate tumor cells without engaging T cells.2

GI=gastrointestinal; HER2=human epidermal growth factor receptor 2.

References


1. Cytryn SL, Janjigian YY. HER2 targeting in esophagogastric cancer: redefining the landscape and breaking barriers. J Natl Compr Canc Netw. 2023;21(4):423-429. doi:10.6004/jnccn.2023.7010 2. Niquille DL, Fitzgerald KM, Gera N. Biparatopic antibodies: therapeutic applications and prospects. MAbs. 2024;16(1):2310890. doi:10.1080/19420862.2024.2310890